The article deals with localization methods of inverse magnetoencephalography tasks. Localization methods are important in real clinical practice. During neurosurgical interventions, various areas of the brain can be damaged, including non-recoverable areas. Since the location of functional areas in the human brain is individual, the doctor must be able to localize these areas in the preoperative period with high accuracy. The developed methods serve the solution of such an important problem.
Keywords:
independent component analysis, magnetoencephalography, current dipole
The article deals with the task of testing drugs for bioequivalence. Bioequivalence studies underlie the reproduction of drugs that have confirmed their efficacy and safety. The main method for testing the bioequivalence hypothesis is the procedure of two one-way Schuirmann tests. Due to inaccurate data, as well as omitted data at the drug trial stage, the Schuirmann criterion allows for errors that exceed a given probability of error of the first kind. Such situations are dangerous for patients who may receive a drug that is not equivalent to the original drug. The authors presented a new criterion that is more sensitive to differences in characteristics affecting the bioavailability of drugs, which reduces patient risk. Note that the new criterion generalizes the
classical Schuirmann criterion, preserving its useful properties.